The European Medicines Agency (EMA) has issued a drug safety signal (pdf) regarding the potential risk of thyroid cancer associated with certain classes of medications that include semaglutide, the active ingredient in the widely used drugs Ozempic, approved for Type 2 diabetes, and Wegovy, approved for obesity.
The medications in question are glucagon-like peptide-1 (GLP-1) receptor agonists. Their manufacturers, including Novo Nordisk, AstraZeneca, Eli Lilly, and Sanofi Winthrop, must submit supplementary information by July 26, 2023.
A safety signal does not necessarily imply a direct causal relationship between a medicine and the reported adverse event. The purpose of assessing safety signals is to determine whether such a causal link exists between the medication and the reported adverse event….