100 years ago, ketogenic diets, which typically provide less than 10% of the daily energy intake as carbohydrates, first entered the realm of modern medicine with their demonstrated effectiveness in reducing or reversing pediatric seizures at the Mayo Clinic. While this remains valid today, there is a lingering concern that the necessary high fat intake when a ketogenic diet is followed long-term represents an undue risk for cardiovascular (heart) disease. This concern has been a persistent barrier to the broader use of the ketogenic diet. In fact, a recent position statement from the American Heart Association (AHA) stated: “There is insufficient evidence to support any existing popular or fad diets such as the ketogenic diet and intermittent fasting to promote heart health.” Unrecognized by this AHA Review Committee and the 2020 Dietary Guidelines Advisory Committee is a substantial and highly cited body of published research demonstrating that a well-formulated ketogenic diet followed for durations ranging …