A collaborative research team from Hong Kong Baptist University and Polytechnic University has synthesized a nanoparticle called TRZD, which can simultaneously diagnose and treat gliomas in the brain. The research results have been published in the international scientific journal Science Advances.
Gliomas are the most common primary brain malignancies, accounting for approximately one third of all brain tumors. Magnetic resonance imaging (MRI) is most commonly used for diagnosing gliomas. But due to its limited sensitivity (in the spatial resolution and short penetration depth), it is usually not able to detect cerebellar gliomas until after the appearance of clinical symptoms.
For the treatment of gliomas, doxorubicin is an effective chemotherapy drug, but it may damage normal cells and cause a series of side effects….