MADRID—A Spanish fishing boat sank Tuesday off Newfoundland, in eastern Canada, killing at least four people, Spain’s maritime rescue service said. Three crew members were rescued and 15 others were missing. Search operations were ongoing to locate other members of the 22-strong crew of the sunken vessel, Spanish government spokeswoman Isabel Rodríguez said, adding that authorities were following the incident “with concern.” A Canadian helicopter had reached the area, which is about 450 kilometers (280 miles) off the island of Newfoundland, and a rescue vessel was on the way to the site, a spokeswoman of the Spanish rescue service said. The boat, called Villa de Pitanxo, operates out of northwest Spain’s Galicia region and sank around 0600 GMT (1 a.m. EST) in rough seas, the regional representative of the Spanish government, Maica Larriba, told Spanish public radio. She said that the crew included 12 Spaniards, eight Peruvians, and two from …