One of the remarkable observations about SARS-CoV-2 infection is the clinical manifestation of venous and arterial thrombosis.
Multiple studies have described thrombotic complications of the infection including stroke, myocardial infarction, systemic arterial embolism, and deep venous thrombosis with pulmonary embolism. In my practice I have seen virtually every one of these complications. De Michele and colleagues studied patients with COVID-19 in 2020, before there were vaccines for the population.[i] They found SARS-CoV-2 Spike protein directly attached to platelets within the blood clots retrieved from patients. Importantly, there was no evidence of the entire virus. This suggests the Spike protein disassociates from the virus and becomes its own clot forming missile within the human body. I could anticipate that mRNA, adenoviral DNA, and Spike protein antigen-based vaccines act the same way by generating free Spike protein within plasma which is able to circulate and participate in the development of blood clots….
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