Millions of Thanksgiving travelers may have to contend with wet and snowy weather as they head to their final destinations for the holidays this week, according to the Weather Prediction Center (WPC). In it’s Nov. 22 weather bulletin, the center said that holiday travelers will be thankful as Thanksgiving week kicks off on a “tranquil note across much of the Lower 48 states.” However, the tranquil weather will later give way to an “active period” for portions of the Southern Plains and Mississippi Valley by midweek. More than 53 million Americans are expected to travel this Thanksgiving, an increase of 13 percent from last year and bringing fall travel back to pre-pandemic levels. According to the American Automobile Association, 48.3 million travelers are expected to reach their destination via automobile and 4.2 million by airplane. With 6.4 million more people traveling this Thanksgiving, along with the recent opening of the U.S. borders to …