SAN DIEGO—E-cigarettes alter the inflammatory state of multiple organs in the body, which can influence how they respond to infections, according to a report published Tuesday by researchers at University of California–San Diego (UCSD) School of Medicine. Daily use of pod-based e-cigarettes alters inflammation in multiple organ systems including the brain, heart, lungs, and colon, the researchers found. Effects also vary depending on the e-cigarette flavor, and can influence how organs respond to infections, such as SARS-CoV-2. The study, published Tuesday in the journal eLife, is the first to assess JUUL devices and their flavorants in a multi-organ fashion. “These pod-based e-cigarettes have only become popular in the last five or so years, so we don’t know much about their long-term effects on health,” said senior study author Dr. Laura Crotty Alexander, associate professor of medicine at UCSD School of Medicine and section chief of pulmonary critical care at Veterans …