One of the two COVID-19 vaccines approved for use in the United States caused facial swelling for people with cosmetic facial fillers. According to information presented during this month’s meeting of a Food and Drug Administration (FDA) panel on Moderna’s COVID-19 vaccine, two of four serious adverse events related to the vaccine in a phase 3 clinical trial happened to patients with the fillers, which are gel-like substances injected beneath the skin to help create a smoother and/or fuller appearance in the face. One trial participant received the injection two weeks prior to getting vaccinated. The other received it six months prior to the shot. Both experienced facial swelling. The swelling was related to the vaccine, according to Moderna and an investigator. “It is possible the localized swelling in these cases is due to an inflammatory reaction from interaction between the immune response after vaccination and the dermal filler. This …