A preclinical study led by researchers from Monash University has discovered that a combination of phage and antibiotic therapy may be the most effective to combat antibiotic-resistant bacteria.
“We have been able to confirm that, even in complex living systems, treatment with our characterised phages can reliably steer bacteria towards a phage-resistant variant that is re-sensitised to antibiotics,” said study author Dr Jeremy Barr on May 8.
Phage therapy is the use of bacteriophages, also known as viruses that kill bacteria to clear a bacterial infection, and in recent years there has been a growing interest in the use of the therapy as a potential treatment for antibiotic-resistant superbugs.
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