Autism is a complex neurodevelopmental disorder whose incidence has been rising dramatically in the past two decades, in step with the dramatic rise in the use of glyphosate (the active ingredient in the pervasive herbicide Roundup) on core food crops [1, 2]. While correlation does not necessarily mean causation, there are multiple mechanisms by which glyphosate’s disruption of human biology, and the biology of the gut microbiome, could cause many of the observed symptoms and biological metrics associated with autism [3, 4]. Remarkably, mice can acquire a syndrome that looks a great deal like human autism, and researchers have been able to create multiple breeds of “designer mice” that exhibit autism–like socio–communicative deficits. These mouse strains have turned out to be very useful for helping us understand the pathology of human autism, even though the mapping is not perfect. One such strain is a naturally occurring inbred strain known as …