Black seed oil has been used for its therapeutic benefits for thousands of years. Since the pandemic began, researchers have been evaluating the effect it may have on COVID-19. The seeds come from the Nigella sativa (N. sativa) plant that grows in Southern Europe, Southwest Asia, and the Middle East. Traditional medicine healers have used the seeds in different forms. Black seed is coal-black with a dull surface and shaped like tiny Brazil nuts. The bioactive components include thymoquinone, alpha-hederin, alkaloids, and omega-6 fatty acids. Black seed oil has also been used for dermatological applications. For example, a review of the literature in the Journal of Dermatology & Dermatologic Surgery found black seed oil could promote wound healing in farm animals and reduce the effects of vitiligo in lizards. In one clinical study in humans, lotion infused with 10 percent of N. sativa oil reduced acne vulgaris after two months, …