Commentary Scientific research is composed of several fundamental elements. Without these core steps, the results of any experiment should be considered questionable, if not outright invalid. These elements include making observations, forming a hypothesis, designing and conducting experiments, documenting the results, and sharing all the data so that the work can be peer-reviewed and replicated. The final element, sharing the data so that the experiment can be reviewed and replicated by other scientists, is at the heart of a final Environmental Protection Agency (EPA) rule to increase the transparency requirements of dose-response regulation. In essence, the Strengthening Transparency in Regulatory Science rule limits the scientific studies the EPA can use to guide regulations, “restricting the use of research that can’t be reproduced or is based on underlying data that isn’t public,” per Bloomberg. It focuses on research that analyzes “the quantitative relationship between the amount of dose or exposure to a pollutant, contaminant, …