Vaccine developers at the National Institute of Allergy and Infectious Diseases (NIAID) are enrolling healthy adult Americans to test an experimental universal influenza vaccine using mRNA technology.
The Phase 1 trial will be conducted at Duke University in Durham, North Carolina, the NIAID said on Monday. Researchers will test the experimental vaccine, dubbed H1ssF-3928 mRNA-LNP, for safety and its ability to induce an immune response.
For this early-stage trial, the federal research agency is looking for up to 50 healthy volunteers aged 18 through 49. There will be three 10-participant groups receiving 10, 25, and 50 micrograms of the experimental vaccine, respectively. After evaluation of the data to determine an optimum dosage, an additional 10 participants will be administered with the optimum dosage….