Researchers at the Hong Kong University of Science and Technology (HKUST) have developed a novel technology for simultaneous genomic DNA and RNA sequencing in single cells from frozen and fresh tissues and identified rare brain tumor cell “spies” disguised as normal cells using this method.
This breakthrough advances cancer research for some of the most complex and rare tumors, opening new directions for future drug target discovery.
Genomic DNA and RNA sequencing are crucial for determining the cancer treatment, as it offers important information about tumor genomic and molecular composition, or cellular heterogeneity, which influences the disease pathology as well as the tumor’s ability to develop drug resistance….