In April 2020, a group of doctors at Strasbourg University Hospital in France published a letter in the New England Journal of Medicine (NEJM) on a study of 58 ICU patients with severe SARS-CoV-2 infection during the one-month period from March 3 to April 3, 2020. Out of the 58 ICU patients, 40 showed agitation, while 26 of the 40 agitated patients had confusion according to the Confusion Assessment Method for the ICU. Overall, the patients not only exhibited respiratory problems, but also neurologic disorders, from agitation and confusion to transient ischemic attack, partial epilepsy, and mild cognitive impairment. 
The main author of the letter, Julie Helms, M.D., Ph.D., also told the BBC that what’s more alarming is that many of these patients were young people in their 30s and 40s….