Probably the broadest, most practical advancement that has come from our response to the pandemic is not a drug or vaccine from Operation Warp Speed, rather it’s an understanding the SARS-CoV-2 like all upper respiratory tract viral infections starts in the nasopharynx and can be treated topically at the source.1 Everyone is familiar with nasal and oral swab testing for COVID-19.  It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the prior strains of the virus.  Thus, there is a wonderful opportunity to reduce viral replication, in fact, kill viruses with agents directly applied in the nasal cavity and the back of the throat….